晏晶
苏州大学附属第二医院
E-mail：jyan@suda.edu.cn
个人简介：
晏晶为苏州大学附属第二医院硕士生导师，入选苏州市姑苏卫生人才计划（C类特聘人才）。围绕药物控制释放体系构建、肿瘤微环境调控及炎症免疫调控开展研究，发表SCI论文20余篇，其中以第一作者及共同通讯作者身份在Adv. Mater., Chem. Eng. J., Biomaterials等知名期刊发表论文10余篇。目前主持国家自然科学基金青年项目（C类）和江苏省自然科学基金青年项目各1项，参与国家重点研发计划项目课题1项。
研究方向：
1. 智能响应型纳米药物构建及肿瘤微环境调控
2. 靶向纳米系统与炎症免疫稳态调控
代表性论文（#代表共同第一作者，*代表通讯作者）：
1. H. Ye#, J. Yan#, Y. Zhou, C.L. Ge, L. Zhong, J. Wang, K.M. Cai, J.J. Cheng, Z.C. Zhou*, L.C. Yin*, Potentiating antibody-dependent cell-mediated cytotoxicity via tumor-specific anchoring and activation of nano-haptens, Adv. Mater. 2026, e72782.
2. L.C. Xie, D.D. Liu, Z.Y. Liu, Y.H. Wang, H.Y. Zhang, J.W. Zhuang, H. Ye, Y. Zhou, Z.P. Wang*, J. Yan*, L.C. Yin*, Immuno-neuroprotectants facilitate neurological recovery via sequestration of neutrophil extracellular traps (NETs) and promotion of neuroregeneration, Adv. Mater. 2025, 38, e18580.
3. H. Ye#, J. Yan#, C.L. Ge, F. Wu, J.L. Zhu, M.Y. Yin, L.C. Xie, Z.C. Zhou*, L.C. Yin*, Tumoral/exosomal PD-L1 silencing reinforces mild photothermal therapy by relieving systemic and local immunosuppression, Chem. Eng. J. 2024, 483, 149093.
4. C. Wu#, J. Yan#, C.L. Ge, L.C. Xie, Y.J. He, Z.Y. Zhao, Y.K. Deng, Q.R. Dong*, L.C. Yin*, Macrophage membrane-reversibly camouflaged nanotherapeutics accelerate fracture healing by fostering MSCs recruitment and osteogenic differentiation, J. Nanobiotechnol. 2024, 22, 411.
5. J.J. Dang, Y.J. Li, J. Yan*, J. Wu, K.M. Cai, L.C. Yin*, Z.C. Zhou*, Reversal of chemoresistance via staged liberation of chemodrug and siRNA in hierarchical response to ROS gradient, Adv. Healthc. Mater. 2024, 13, 2304130.
6. J. Yan#, X. Liu#, F. Wu, C.L. Ge, H. Ye, X.Y. Chen, Y.S. Wei, R.X. Zhou, S.Z. Duan, R.Y. Zhu, Y.R. Zheng, L.C. Yin*, Platelet pharmacytes for the hierarchical amplification of antitumor immunity in response to self-generated immune signals, Adv. Mater. 2022, 34, 2109517.
7. M. Lan, M.Y. Hou, J. Yan*, Q.R. Deng, Z.Y. Zhao, S.X. Lv, J.J. Dang, M.Y. Yin, Y. Ji*, L.C. Yin*, Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury, Nano Res. 2022, 15, 9125–9134.
8. J. Yan, Q.H. Wu, Z.Y. Zhao, J.H. Wu, H. Ye, Q.J. Liang, Z.C. Zhou, M.Y. Hou, X.D. Li, Y. Liu*, L.C. Yin*, Light-assisted hierarchical intratumoral penetration and programmed antitumor therapy based on tumor microenvironment (TME)-amendatory and self-adaptive polymeric nanoclusters, Biomaterials 2020, 255, 120166.
9. J. Yan, R.Y. Zhu, F. Wu, Z.Y. Zhao, H. Ye, M.Y. Hou, Y. Liu*, L.C. Yin*, iRGD-reinforced, photo-transformable nanoclusters toward cooperative enhancement of intratumoral penetration and antitumor efficacy, Nano Res. 2020, 12, 2706–2715.
10. J. Yan, D.W. Zhang, H.Y. Yu, L.L. Ma, M.X. Deng, Z.H. Tang*, X.F. Zhang*, Patupilone-loaded poly(L-glutamic acid)-graft-methoxy-poly(ethylene glycol) micelle for oncotherapy, J. Biomater. Sci., Polym. Ed. 2017, 28, 394-414.