熊国军

发布者:朱苏静发布时间:2026-03-16浏览次数:10



  熊国军 博士

  苏州大学优秀青年学者(讲师)

  邮箱:gjxiong@suda.edu.cn

 

 

 个人简介:

熊国军,2023年于伦敦大学学院(UCL)获哲学博士学位,同年留校从事博士后研究至2026年。研究方向为蛋白基纳米药物靶向递送、难溶性抗肿瘤药物制剂创新及转化医学。以独立第一作者在Journal of Controlled Release、Drug Delivery、International Journal of Pharmaceutics等药学主流期刊发表SCI论文5篇;申报英国专利及国际PCT专利各1项;主持UCLB支持转化科研项目2项;参与Elsevier、Springer Nature英文专著编写2部。

 

研究方向:

开发难溶性药物、生物大分子及金属药物的纳米制剂

构建蛋白基纳米载体的靶向递送系统

探索肿瘤干细胞靶向疗法

推动抗癌纳米药物的临床转化研究

 

代表性论文:

[1] G. Xiong, A. Vaideanu, R.D. Mellor, C. Jiang, B. Gardner, N. Stone, A.G. Schätzlein, I.F. Uchegbu, A Renally Excretable Gold Nanoparticle Oncology Platform Enabling Effective Photothermal Therapy and Chemotherapy Combination, ACS Nano Med. (2026) acsnanomed.5c00114. https://doi.org/10.1021/acsnanomed.5c00114.

[2] G. Xiong, C. Jiang, A.G. Schätzlein, I.F. Uchegbu, The colloidal stability of albumin-based drug delivery systems has a profound effect on tumoricidal activity, Drug Delivery 33 (2026) 2614801. https://doi.org/10.1080/10717544.2026.2614801.

[3] G. Xiong, S. Li, A.G. Schätzlein, I.F. Uchegbu, Albumin-based nanoparticles encapsulating SN-38 demonstrate superior antitumor efficacy compared to irinotecan, Drug Delivery 32 (2025) 2545519. https://doi.org/10.1080/10717544.2025.2545519.

[4] G. Xiong, S. Li, A.G. Schätzlein, I.F. Uchegbu, Amphiphilic albumin-based nanoparticles designed for the efficient delivery of taxanes, International Journal of Pharmaceutics (2025) 125965. https://doi.org/10.1016/j.ijpharm.2025.125965.

[5] G. Xiong, A.G. Schätzlein, I.F. Uchegbu, Acetyl-lysine human serum albumin nanoparticles activate CD44 receptors, with preferential uptake by cancer stem cells, leading to tumor eradication, Journal of Controlled Release 382 (2025) 113632. https://doi.org/10.1016/j.jconrel.2025.113632.

[6] R. Mellor, G. Xiong, A. Vaideanu, B. Gardner, N. Stone, A. Schätzlein, I. Uchegbu, Clustered, SERS-Active, Ultrasmall AuNPs for Photothermal Therapy, International Journal of Nanomedicine Volume 20 (2025) 8209–8220. https://doi.org/10.2147/ijn.s513400.

[7] G. Xiong, I.F. Uchegbu, Nanoparticles and Cancer Chemotherapy, in: I.F. Uchegbu, A.G. Schätzlein, A. Lalatsa, D.R.S. Lopez (Eds.), Fundamentals of Pharmaceutical Nanoscience, Springer Nature Switzerland, Cham, 2024: pp. 423–449. https://doi.org/10.1007/978-3-031-59478-6_16.