
姓 名:王从周
职称职务:特聘教授、博士生导师
电子邮箱:czwang12@suda.edu.cn
个人简介:
王从周,2026年6月加入苏州大学国际创新药学院,任特聘教授,国家级重大人才工程入选者。华侨大学制药工程学士(2009年),重庆大学药学硕士(2012年),美国弗吉尼亚联邦大学化学与生命科学工程博士(2015年),美国华盛顿大学圣路易斯分校材料与机械工程系博士后(2016-2018年)。2018至2023年期间,他在美国南达科他矿业理工大学,纳米科学与生物医学工程系,任助理教授(Tenure-track assistant professor);2023至2026年期间在美国南达科他矿业理工大学,纳米科学与生物医学工程系,任副教授(Tenured associate professor)。
王从周团队近5年来专注于纳米材料与细胞、蛋白质的相互作用及其应用。王从周作为通讯作者近5年在ACS Nano, Biomaterials, Chemical Engineering Journal, Nano Letters等期刊发表论文16篇;申请国际/美国专利4项,已授权2项;与美国航空航天局等5家单位企业合作推进基于纳米生物技术的疾病诊疗;作为独立PI总计获得150万美元研究经费,包括美国国家科学基金委青年教授奖项NSF CAREER Award和美国国立卫生院NIH R15等项目;连续多年受邀担任美国国立卫生院基金评委。
研究方向:
1. 纳米生物力学,纳米毒理学,细胞表型转化;
2. 纳米剂型用于抑制肿瘤迁移和耐药性;
3. 纳米剂型用于改善动脉粥样硬化;
4. 纳米剂型用于逆转器官纤维化;
5. 原子力显微术;
6. 纳米多孔材料用于蛋白质保存
代表性论文(*代表通讯作者):
成立独立课题组以来:
1. X. Yu, S. Smith, C. Wang*, “Reversing fibroblast-to-myofibroblast transition using surface-engineered nanoparticles to potentially ameliorate fibrotic diseases”, Biomaterials, 2026, 328,123829.
2. X. Luo, X. Yu, V. Kee, S. Smith, C. Wang*, “Inhibiting migration of endothelial-derived mesenchymal cells using a nanoparticle-based photothermal treatment impedes atherosclerosis and cancer progression”, ACS Applied Materials and Interfaces, 2026, 18, 7938-7949.
3. X. Yu, K. Ballard, C. Collier, X, Wei, S. Ning*, C. Wang*, “Targeting and disrupting cytoskeleton using core-shell metal-organic framework nanoparticles to inhibit cancer cell migration”, Journal of Colloid and Interface Science, 2026, 704, 139298.
4. J. Liu, X. Yu, X. Luo, Z. Yang, N Zhang, S. Ning*, C. Wang*, “Nanoparticle and photothermal mediated mesenchymal-epithelial transition in cancer cells to slow cancer cell migration”, Chemical Engineering Journal, 2025, 164286.
5. J. Liu, S. Smith, C. Wang*, “Mild photothermal therapy for cancer cell modulation: A transformative approach to regulate cancer cell phenotype and enhance therapeutic outcomes”, Journal of Pharmaceutical Analysis, 2025, 101185.
6. J. Liu, X. Yu, A. Braucht, S. Smith, C. Wang*, “N-cadherin targeted melanin nanoparticles reverse the endothelial-mesenchymal transition in vascular endothelial cells to potentially slow the progression of atherosclerosis and cancer”, ACS Nano, 2024, 8, 8229-8247.
7. X. Yu, J. Liu, A. Bauer, X. Wei, S. Smith, S. Ning*, C. Wang*, “Enhancing tumor endothelial permeability using MUC18-targeted gold nanorods and mild hyperthermia”, Journal of Colloid and Interface Science, 2024, 676, 101-109.
8. J. Liu, S. Smith, C. Wang*, “Photothermal Attenuation of Cancer Cell Stemness, Chemoresistance, and Migration Using CD44-Targeted MoS2 Nanosheets”, Nano Letters, 2023, 23,1989–1999.
9. Z. Li, J. Liu, K. Ballard, C. Liang*, C. Wang*, “Low-dose albumin-coated gold nanorods induce intercellular gaps on vascular endothelium by causing the contraction of cytoskeletal actin”, Journal of Colloid and Interface Science, 2023, 649, 844-854.
10. J. Liu, A. Rickel, S. Smith, Z. Hong*, C. Wang*, “Non-cytotoxic doses of metal-organic framework nanoparticles increase endothelial permeability by inducing actin reorganization”, Journal of Colloid and Interface Science, 2023, 634, 325-335.
11. J. Liu, S. Smith, C. Wang*, “Reversing the epithelial-mesenchymal transition in metastatic cancer cells using CD146-targeted black phosphorus nanosheets and a mild photothermal treatment”, ACS Nano, 2022, 16, 3208–3220.
12. J. Liu, L. Kang, S. Smith, C. Wang*, “Transmembrane MUC18 targeted polydopamine nanoparticles and a mild photothermal effect synergistically disrupt actin cytoskeleton and migration of cancer cells”, Nano Letters, 2021, 21, 9609–9618.
13. D. Kota, L. Kang, A. Rickel, J. Liu, S. Smith, Z. Hong*, C. Wang*, "Low doses of zeolitic imidazolate framework-8 nanoparticles alter the actin organization and contractility of vascular smooth muscle cells," Journal of Hazardous Materials, 2021, 414, 125514.
14. J. Liu, L. Kang, P. Ahrenkiel, S. Smith, C. Wang*, “Targeting cancer cell adhesion molecule, CD146, with low-dose gold nanorods and mild hyperthermia disrupts actin cytoskeleton and cancer cell migration”, Journal of Colloid and Interface Science, 2021, 601, 556-569.
15. L. Kang, S. Smith, C. Wang*, "Stabilization of surface-bound antibodies for ELISA based on a reversable zeolitic imidazolate framework-8 coating," Journal of Colloid and Interface Science, 2021, 588, 101-109.
16. L. Kang, S. Smith, C. Wang*, "Metal-organic framework preserves biorecognition of antibodies on nanoscale surfaces validated by single molecule force spectroscopy," ACS Applied Materials & Interfaces, 2020, 12, 3011-3020.
作为学生及博士后:
1. C Wang, G Sudlow, Z Wang, S Cao, Q Jiang, A Neiner, J Morrissey, E Kharasch, S Achilefu, S Singamaneni*, “Metal organic framework encapsulation preserves the bioactivity of protein therapeutics”, Advanced Healthcare Materials, 2018, 7, 1800950.
2. C Wang, H Sun, J Luan, Q Jiang, S Tadepalli, J Morrissey, E Kharasch, S Singamaneni*, “Metal-organic framework encapsulation for biospecimen preservation”, Chemistry of Materials, 2018, 30, 1291-1300.
3. C Wang, L Wang, S Tadepalli, J Morrissey, E Kharasch, R Naik*, S Singamaneni*, “Ultra-robust biochips with metal-organic framework coatings for point-of-care diagnosis”, ACS Sensors, 2018, 3, 342-351.
4. C Wang, S Tadepalli, J Luan, K Liu, J Morrissey, E Kharasch, R Naik*, S Singamaneni*, “Metal-organic framework as a protective coating for biodiagnostic chips”, Advanced Materials, 2017, 29, 1604433.
5. C Wang, R Hu, J Morrissey, E Kharasch, S Singamaneni*, “Single molecule force spectroscopy to compare natural versus artificial antibody-antigen interaction”, Small, 2017, 13, 1604255.
6. C Wang, C Stanciu, C Ehrhardt, V Yadavalli*, “Nanoscale characterization of forensically relevant epithelial cells and surface associated extracellular DNA”, Forensic Science International, 2017, 277, 252-258.
7. C Wang, J Luan, S Tadepalli, K Liu, J Morrissey, E Kharasch, R Naik*, S Singamaneni*, “Silk-encapsulated plasmonic biochips with enhanced thermal stability”, ACS Applied Materials & Interfaces, 2016, 8, 26493-26500.
8. C Wang, O Zolotarskaya, S Nair, C Ehrhardt, D Ohman, K Wynne, V Yadavalli*, “Real-time observation of antimicrobial polycation effects on Escherichia coli: adapting the carpet model for membrane disruption to quaternary copolyoxetanes”, Langmuir, 2016, 32, 2975-2984.
9. C Wang, C Ehrhardt, V Yadavalli*, “Nanoscale imaging and hydrophobicity mapping of the antimicrobial effect of copper on bacterial surfaces”, Micron, 2016, 88, 16-23.
10. C Wang, C Stanciu, C Ehrhardt, V Yadavalli*, “Evaluation of whole cell fixation methods for the analysis of nanoscale surface features of Yersinia pestis KIM”, Journal of Microscopy, 2016, 263, 260-267.
11. C Wang, C Stanciu, C Ehrhardt, V Yadavalli*, “The effect of growth temperature on the nanoscale biochemical surface properties of Yersinia pestis”, Analytical and Bioanalytical Chemistry, 2016, 408, 5585-5591.
12. C Wang, Y Jin, U Desai, V Yadavalli*, “Investigation of the heparin-thrombin interaction by dynamic force spectroscopy”, Biochimica et Biophysica Acta, 2015, 1850, 1099-1106.
13. C Wang, C Ehrhardt, V Yadavalli*, “Single cell profiling of surface carbohydrates on Bacillus cereus”, Journal of the Royal Society Interface, 2015, 12, 20141109.
14. C Wang, C Stanciu, C Ehrhardt, V Yadavalli*, “Morphological and mechanical imaging of Bacillus cereus spore formation at the nanoscale”, Journal of Microscopy, 2015, 258, 49-58.
15. C Wang, V Yadavalli*, “Spatial recognition and mapping of proteins using DNA aptamers”, Nanotechnology, 2014, 25, 455101.
16. C Wang, V Yadavalli*, “Investigating biomolecular recognition at the cell surface using atomic force microscopy”, Micron, 2014, 60, 5-17.
17. C Wang, J Wang*, L Deng, “Evaluating interaction forces between BSA and rabbit anti-BSA in sulphathiazole sodium, tylosin and levofloxacin solution by AFM”, Nanoscale Research Letters, 2011, 6,579.
招生需求(博士后,博士,硕士):
欢迎具备药学、生物材料、生物医学工程等相关背景的同学申请,拥有研究经历(如纳米医学,细胞培养,动物实验,原子力显微镜)的同学优先。对学生的期望:希望申请人对研究感兴趣,有激情,有良好的学习和科研习惯,热爱运动。对学生的承诺:作为你的导师和并肩作战的同事,你会得到全面的关注和培养。你会学到如何设计实施实验,如何快速有效撰写科研论文,如何在英文环境中自信交流等。欢迎发送简历+姓名+申请位置至czwang12@suda.edu.cn