Topic: Molecular engineering RNAs for research and therapy
Speaker: Professor Yu Aiming (University of California, Davis, USA)
Time: 9:00-10:00, July 20, 2023
Location: Conference Room 2108, Yunxuan Building
About the speaker
Dr. Yu is currently a professor in the Department of Biochemistry and Molecular Medicine at the University of California, Davis, School of Medicine, and director of the Shared Resource Laboratory of Molecular Pharmacology at the Cancer Research Center. He was an associate professor of pharmacology at the College of Pharmacy, University at Buffalo, State University of New York. He took the lead in combinatorial chemistry research in China. After coming to the United States, he developed and used new technical methods and models (including transgenic mice) to discover for the first time the importance of CYP2D6 metabolic enzymes in the metabolism of serotonin drugs and made pioneering discoveries in the study of CYP2D6's genetic and pharmacological molecular mechanism and endogenous metabolism. Prof. Yu has pioneered a new field of research on the regulation of drug-metabolizing enzymes and membrane proteins by small RNAs. A novel engineering technique for RNA biosynthesis has recently been developed. Prof. Yu has published more than 160 papers and 4 granted patents. Current research interests and main topics include small RNA regulation of drugs and endogenous metabolism and RNA drug development.