Jin Yan
Associate Researcher
The Second Affiliated Hospital, Soochow University
E-mail：jyan@suda.edu.cn
Biography：
Jing Yan is an Associate Researcher and Master’s Supervisor at the Second Affiliated Hospital of Soochow University. She has been recognized under the Suzhou Gusu Health Talent Program as a Class C Distinguished Talent. Her research focuses on the development of drug controlled release systems, modulation of the tumor microenvironment, and regulation of inflammatory and immune responses. She has authored over 20 SCI publications, with more than 10 papers as first or co-corresponding author in journals such as Advanced Materials, Chemical Engineering Journal, and Biomaterials. She is currently leading a project funded by the National Natural Science Foundation of China (Youth Program, Class C) and a Jiangsu Provincial Natural Science Foundation Youth Project, while also participating in a National Key Research and Development Program project.
Selected Publications (# represents co-first author, * represents corresponding author)：
1. H. Ye#, J. Yan#, Y. Zhou, C.L. Ge, L. Zhong, J. Wang, K.M. Cai, J.J. Cheng, Z.C. Zhou*, L.C. Yin*, Potentiating antibody-dependent cell-mediated cytotoxicity via tumor-specific anchoring and activation of nano-haptens, Adv. Mater. 2026, e72782.
2. L.C. Xie, D.D. Liu, Z.Y. Liu, Y.H. Wang, H.Y. Zhang, J.W. Zhuang, H. Ye, Y. Zhou, Z.P. Wang*, J. Yan*, L.C. Yin*, Immuno-neuroprotectants facilitate neurological recovery via sequestration of neutrophil extracellular traps (NETs) and promotion of neuroregeneration, Adv. Mater. 2025, 38, e18580.
3. H. Ye#, J. Yan#, C.L. Ge, F. Wu, J.L. Zhu, M.Y. Yin, L.C. Xie, Z.C. Zhou*, L.C. Yin*, Tumoral/exosomal PD-L1 silencing reinforces mild photothermal therapy by relieving systemic and local immunosuppression, Chem. Eng. J. 2024, 483, 149093.
4. C. Wu#, J. Yan#, C.L. Ge, L.C. Xie, Y.J. He, Z.Y. Zhao, Y.K. Deng, Q.R. Dong*, L.C. Yin*, Macrophage membrane-reversibly camouflaged nanotherapeutics accelerate fracture healing by fostering MSCs recruitment and osteogenic differentiation, J. Nanobiotechnol. 2024, 22, 411.
5. J.J. Dang, Y.J. Li, J. Yan*, J. Wu, K.M. Cai, L.C. Yin*, Z.C. Zhou*, Reversal of chemoresistance via staged liberation of chemodrug and siRNA in hierarchical response to ROS gradient, Adv. Healthc. Mater. 2024, 13, 2304130.
6. J. Yan#, X. Liu#, F. Wu, C.L. Ge, H. Ye, X.Y. Chen, Y.S. Wei, R.X. Zhou, S.Z. Duan, R.Y. Zhu, Y.R. Zheng, L.C. Yin*, Platelet pharmacytes for the hierarchical amplification of antitumor immunity in response to self-generated immune signals, Adv. Mater. 2022, 34, 2109517.
7. M. Lan, M.Y. Hou, J. Yan*, Q.R. Deng, Z.Y. Zhao, S.X. Lv, J.J. Dang, M.Y. Yin, Y. Ji*, L.C. Yin*, Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury, Nano Res. 2022, 15, 9125–9134.
8. J. Yan, Q.H. Wu, Z.Y. Zhao, J.H. Wu, H. Ye, Q.J. Liang, Z.C. Zhou, M.Y. Hou, X.D. Li, Y. Liu*, L.C. Yin*, Light-assisted hierarchical intratumoral penetration and programmed antitumor therapy based on tumor microenvironment (TME)-amendatory and self-adaptive polymeric nanoclusters, Biomaterials 2020, 255, 120166.
9. J. Yan, R.Y. Zhu, F. Wu, Z.Y. Zhao, H. Ye, M.Y. Hou, Y. Liu*, L.C. Yin*, iRGD-reinforced, photo-transformable nanoclusters toward cooperative enhancement of intratumoral penetration and antitumor efficacy, Nano Res. 2020, 12, 2706–2715.
10. J. Yan, D.W. Zhang, H.Y. Yu, L.L. Ma, M.X. Deng, Z.H. Tang*, X.F. Zhang*, Patupilone-loaded poly(L-glutamic acid)-graft-methoxy-poly(ethylene glycol) micelle for oncotherapy, J. Biomater. Sci., Polym. Ed. 2017, 28, 394-414.
